miR-30c-5p Reduces Renal Ischemia-Reperfusion Involving Macrophage
نویسندگان
چکیده
منابع مشابه
Antithrombin reduces ischemia/reperfusion-induced renal injury in rats
http://bloodjournal.hematologylibrary.org/content/101/8/3029.full.html Updated information and services can be found at: (973 articles) Phagocytes (2497 articles) Hemostasis, Thrombosis, and Vascular Biology Articles on similar topics can be found in the following Blood collections http://bloodjournal.hematologylibrary.org/site/misc/rights.xhtml#repub_requests Information about reproducin...
متن کاملAtorvastatin Protects Myocardium Against Ischemia-Reperfusion Injury Through Inhibiting miR-199a-5p.
OBJECTIVE This study aimed to evaluate the protective effects of atorvastatin against myocardial ischemia/reperfusion (I/R) injury in cardiomyocytes and its possible underlying mechanism. METHOD Direct cytotoxic effect of OGD/R on cardiomyocytes with and without atorvastatin pretreatment was evaluated. Effects of atorvastatin on expression of GSK-3β and miR-199a-5p were determined using RT-PC...
متن کاملmiR-525-5p inhibits ADAMTS13 and is correlated with Ischemia/reperfusion injury-induced neuronal cell death.
The understanding of molecular mechanism underlying ischemia/reperfusion-induced neuronal death and neurological dysfunction may provide therapeutic targets for ischemic stroke. In this study, miR-525-5p is clearly reduced in the ischemic brain after oxygen-glucose deprivation (OGD). Using TargetScan, MicroCosm Targets version 5, and microRNA.org databases, we identified miR-525-5p as a possibl...
متن کاملHIF-1α induction during reperfusion avoids maladaptive repair after renal ischemia/reperfusion involving miR127-3p
Ischemia/reperfusion (I/R) leads to Acute Kidney Injury. HIF-1α is a key factor during organ response to I/R. We previously demonstrated that HIF-1α is induced during renal reperfusion, after ischemia. Here we investigate the role of HIF-1α and the HIF-1α dependent mechanisms in renal repair after ischemia. By interference of HIF-1α in a rat model of renal I/R, we observed loss of expression an...
متن کاملAmelioration of rat renal ischemia/reperfusion injury by L-Nil
Introduction: Ischemia/reperfusion (IR) injury involves a complex interrelated sequence of events. High levels of nitric oxide (NO) are generated with inducible form of nitric oxide synthase (iNOS) leading to the renal IR injury and glutathione (GSH) depletion. The present study was designed to investigate the effect of L-Nil (N6- (1-Iminoethyl)-L- lysine.hydrochloride), a selective inhibito...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Medical Science Monitor
سال: 2019
ISSN: 1643-3750
DOI: 10.12659/msm.914579